"I had a sour stomach, and fatigue and reached a point that I could not get off the couch."

Now, to tell my story I have been on Paxil for 3 1/2 years and when I first started it felt an immediate improvement in my anxiety and depression. My attitude was a noticeable improvement to everyone around me. In the 3 years I tried to take myself off many times. I honestly don't remember all the physical side effects that alot of people have mentioned. But, I did experience extreme mood changes and extreme anxiety and depression. So, like everyone else I decided to go back on. Well, in the last 6 months I felt the PAXIL wasn't helping me. I felt I was (am) entering into a deeper depression. I have extreme fatigue, don't feel like working, much less taking care of my home and 3 children and HAVE NO SEXUAL DESIRE AT ALL. Oh, and not to mention the slow but steady weight gain.

One day I heard an ad on the radio saying "Do you want your sex life back" "Tried of feeling ...." The ad then when on to say that these are part of the long term effects of anti-depressants and gave an 800 number to call to see if you qualified to part of the study. Well, for some reason I did not qualify. But started believing that my lack of interest in sex was due to the Paxil. So in December I have slowly started to wean my self off. Again, I can't pinpoint the all the side effects like many people have mentioned. But, I can say that my depression and fatigue is so extreme all I want to do is sleep!

I have been completely off of Paxil the entire month of February and was forced to go t to my Doctor today and he told switched me to EFFEXOR. I now wonder that my feelings my all be part of the withdrawal problems.

I am remembered a period in December over the course of two weeks where I felt somewhat similar. It was December and that terrible flu was going around and I really thought it was that. But now that I am reading and remembering I don't think it was the flu and believe now it was the "withdrawals". I now remember telling my husband, God, if this is the flu why don't I have a fever like everyone else. I remembering one Monday I had such an extreme headache I took Excedrin PM and slept from 8:00am-3:00pm and the went to bed that evening at 7:00pm. And just like Friday, I had the same flu like symptoms. I had a sour stomach, and fatigue and reached a point that I could not get off the couch. I am getting worried that all these flu days were not flu days withdrawal side effects.

-- submitted Jane, 37

"On Paxil, I was always sleepy, and would constantly have to take naps."

I spent about 13 months on Paxil and have just switched to Effexor XR. On Paxil, I was always sleepy, and would constantly have to take naps. It was an irresistible urge to lie down and sleep, and really got in the way of a normal daily life. I could no longer drive for more than an hour or two without having to pull over for a nap, and I spent most of my days off on the couch, too tired to go out and do anything. The other main effect I suffered was weight gain -- 30 pounds' worth. Unfortunately, I had mononucleosis when I began taking Paxil for depression, and since mono's symptoms include fatigue and possible weight gain due to less exercise and a slowed-down metabolism, it took my family doctor and myself a long time after my recovery from mono to determine that Paxil might be the culprit causing the weight gain and continuing fatigue. My psychiatrist (who initially prescribed the Paxil and whom I no longer see) dismissed my concerns that I was rapidly gaining weight, even though this had never happened to me before in 30 years. He said Paxil rarely causes weight gain and was more likely to cause weight loss. Skimming through the Disease Management Forum paints a different story. My family doctor has run a battery of tests and ruled out pretty much anything he can think of that would cause this weight gain and fatigue (thyroid, anemia, hepatitis, ect.). That's why he has switched me to Effexor XR, which he says may improve my condition. To be fair, Paxil did get rid of my depression, mood swings and temper, and the only other side effect I experienced, mild sexual dysfunction, was not serious. However, after months of convincing myself that Paxil was a wonder drug (in that it improved my mood so much) I decided I was not willing to continue with the drug if the tradeoff was constant fatigue and steady weight gain. I am now going to Weight Watchers to get rid of those 30 pounds, and after just five days on Effexor, I already more energy and my head is a lot clearer.

-- submitted by anouk, 30

"I have two months on Paxil, I can said that it works on me, it helped with my depression, mood swings and temper"

I have two months on Paxil, I can said that it works on me, it helped with my depression, mood swings and temper but on the side effects I feel very, very tired, I want to sleep all the time.I have also wet hands and some problems to sleep.

I am taking a 1/2 20 gms pill a day , I started with one pill daily, but it was too strong for me I was like a zombie! looking at all in gray color, with eyes of fish and with a dry mouth, looked to everything and said !bah!

I don't want to feel like that all the time! I feel better with out depression but this feeling is disturbing me now!

I read that some people here switched on Effexor Xr to avoid that lack of energy, is there anyone who have done this?

what is the dose that you are taking?

did you waited two weeks to clean your body from paxil?

Thanks in advance for your help and good luck!

--submitted by Carlos, 27